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1

Three-Component Castagnoli–Cushman Reaction of 3-Arylglutaconic Acids with Aromatic Aldehydes and Amines Delivers Rare 4,6-Diaryl-1,6-dihydropyridin-2(3 H )-ones

Firsov, Andrei, Chupakhin, Evgeny, Dar’in, Dmitry, Bakulina, Olga, Krasavin, Mikhail

Journal:

Organic Letters

Year:

2019

Language:

english

File:

PDF, 934 KB

english, 2019

2

Skeletal Diversity in Combinatorial Fashion: A New Format for the Castagnoli-Cushman Reaction

Lepikhina, Anastasia, Dar'in, Dmitry, Bakulina, Olga, Chupakhin, Evgeny, Krasavin, Mikhail

Journal:

ACS Combinatorial Science

Year:

2017

Language:

english

File:

PDF, 466 KB

english, 2017

3

Acetic anhydride to the rescue: Facile access to privileged 1,2,3,4-tetrahydropyrazino[1,2-a]indole core via the Castagnoli-Cushman reaction

Chizhova, Maria, Khoroshilova, Olesya, Dar'in, Dmitry, Krasavin, Mikhail

Journal:

Tetrahedron Letters

Year:

2018

Language:

english

File:

PDF, 1.01 MB

english, 2018

4

New Heterocyclic Product Space for the Castagnoli–Cushman Three-Component Reaction

Dar’in, Dmitry, Bakulina, Olga, Chizhova, Maria, Krasavin, Mikhail

Journal:

Organic Letters

Year:

2015

Language:

english

File:

PDF, 725 KB

english, 2015

5

The rare cis-configured trisubstituted lactam products obtained by the Castagnoli–Cushman reaction in N,N-dimethylformamide

Dar'in, Dmitry, Bakulina, Olga, Nikolskaya, Sofia, Gluzdikov, Ivan, Krasavin, Mikhail

Journal:

Year:

2016

Language:

english

File:

PDF, 373 KB

english, 2016

6

Spirocyclic Amino Alcohol Building Blocks Prepared via a Prins-Type Cyclization in Aqueous Sulfuric Acid

Lukin, Alexey, Bagnyukova, Darya, Kalinchenkova, Natalya, Zhurilo, Nikolay, Krasavin, Mikhail

Journal:

Tetrahedron Letters

Year:

2016

Language:

english

File:

PDF, 576 KB

english, 2016

7

A three-component, Zn(OTf) 2 -mediated entry into trisubstituted 2-aminoimidazoles

Lukin, Alexei, Bakholdina, Anna, Kryukova, Anna, Sapegin, Alexander, Krasavin, Mikhail

Journal:

Beilstein Journal of Organic Chemistry

Year:

2019

Language:

english

File:

PDF, 212 KB

english, 2019

8

Facile Access to 3-Unsubstituted Tetrahydroisoquinolonic Acids via the Castagnoli–Cushman Reaction

Guranova, Natalia, Dar’in, Dmitry, Krasavin, Mikhail

Journal:

Year:

2018

Language:

english

File:

PDF, 196 KB

english, 2018

9

Iron-Complexing Cyclic Hydroxamic Acid Analogs of Bacterial Siderophores Prepared via the Castagnoli-Cushman Reaction of Unprotected Oximes

Bakulina, Olga, Bannykh, Anton, Dar'in, Dmitry, Krasavin, Mikhail

Journal:

Chemistry - A European Journal

Year:

2017

Language:

english

File:

PDF, 1.57 MB

english, 2017

10

Spontaneous formation of tricyclic lactones following the Castagnoli–Cushman reaction

Usmanova, Liliia, Bakulina, Olga, Dar’in, Dmitry, Krasavin, Mikhail

Journal:

Chemistry of Heterocyclic Compounds

Year:

2017

Language:

english

File:

PDF, 512 KB

english, 2017

11

Primary mono- and bis-sulfonamides obtained via regiospecific sulfochlorination of N-arylpyrazoles: inhibition profile against a panel of human carbonic anhydrases

Krasavin, Mikhail, Korsakov, Mikhail, Ronzhina, Oksana, Tuccinardi, Tiziano, Kalinin, Stanislav, Tanç, Muhammet, Supuran, Claudiu T.

Journal:

Journal of Enzyme Inhibition and Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 4.78 MB

english, 2017

12

Gold-Catalyzed Oxidation of Internal Alkynes into Benzils and its Application for One-Pot Synthesis of Five-, Six-, and Seven-Membered Azaheterocycles

Dubovtsev, Alexey Yu., Dar'in, Dmitry V., Krasavin, Mikhail, Kukushkin, Vadim Yu.

Journal:

European Journal of Organic Chemistry

Year:

2019

Language:

english

File:

PDF, 1.23 MB

english, 2019

13

Aldazines in the Castagnoli–Cushman Reaction

Mikheyev, Alexander, Kantin, Grigory, Krasavin, Mikhail

Journal:

Year:

2018

Language:

english

File:

PDF, 262 KB

english, 2018

14

Design, synthesis, and biological evaluation of novel derivatives of dithiodiglycolic acid prepared via oxidative coupling of thiols

Bakulina, Olga, Bannykh, Anton, Jovanović, Mirna, Domračeva, Ilona, Podolski-Renić, Ana, Žalubovskis, Raivis, Pešić, Milica, Dar’in, Dmitry, Krasavin, Mikhail

Journal:

Journal of Enzyme Inhibition and Medicinal Chemistry

Year:

2019

Language:

english

File:

PDF, 1.44 MB

english, 2019

15

The Castagnoli-Cushman reaction in a three-component format

Chupakhin, Evgeny, Dar'in, Dmitry, Krasavin, Mikhail

Journal:

Tetrahedron Letters

Year:

2018

Language:

english

File:

PDF, 747 KB

english, 2018

16

1,4-Diiodo-2,3,5,6-tetrafluorobenzene (DITFB) in the synthesis of polyfluorinated organic compounds

Sapegin, Alexander, Krasavin, Mikhail

Journal:

Journal of Fluorine Chemistry

Year:

2018

Language:

english

File:

PDF, 1.11 MB

english, 2018

17

Modular Assembly of Tunable Fluorescent Chemosensors Selective for Pb 2+ and Cu 2+ Metal Ions via the Multicomponent Castagnoli‐Cushman Reaction

Bakulina, Olga, Rashevskii, Artem, Dar'in, Dmitry, Halder, Sandipan, Khagar, Prerna, Krasavin, Mikhail

Journal:

ChemistrySelect

Year:

2019

Language:

english

File:

PDF, 2.74 MB

english, 2019

18

Bicyclic Piperazine Mimetics of the Peptide beta-Turn Assembled via the Castagnoli-Cushman Reaction

Usmanova, Liliia, Dar'in, Dmitry, Novikov, Mikhail Sergeevich, Gureev, Maxim, Krasavin, Mikhail

Journal:

Journal of Organic Chemistry

Year:

2018

Language:

english

File:

PDF, 701 KB

english, 2018

19

Efficient cyclodehydration of dicarboxylic acids with oxalyl chloride

Kantin, Grigory, Chupakhin, Evgeny, Dar'in, Dmitry, Krasavin, Mikhail

Journal:

Tetrahedron Letters

Year:

2017

Language:

english

File:

PDF, 363 KB

english, 2017

20

1,1′-Carbonyldiimidazole as a cyclodehydrating agent for the Castagnoli–Cushman reaction of dicarboxylic acids and imines

Chupakhin, Evgeny G., Bakulina, Olga Yu., Dar’in, Dmitry V., Krasavin, Mikhail

Journal:

Mendeleev Communications

Year:

2019

Language:

english

File:

PDF, 215 KB

english, 2019

21

o-Phenylenediacetic Acid Anhydride in the Castagnoli–Cushman Reaction: Extending the Product Space to ε-Lactams

Bakulina, Olga, Dar’in, Dmitry, Krasavin, Mikhail

Journal:

Year:

2017

Language:

english

File:

PDF, 894 KB

english, 2017

22

Complications in the Castagnoli-Cushman reaction: An unusual course of reaction between cyclic anhydrides and sterically hindered indolenines

Chizhova, Maria, Dar'in, Dmitry, Krasavin, Mikhail

Journal:

Tetrahedron Letters

Year:

2017

Language:

english

File:

PDF, 787 KB

english, 2017

23

Design, in silico prioritization and biological profiling of apoptosis-inducing lactams amenable by the Castagnoli-Cushman reaction

Krasavin, Mikhail, Gureyev, Maxim A., Dar'in, Dmitry, Bakulina, Olga, Chizhova, Maria, Lepikhina, Anastasia, Novikova, Daria, Grigoreva, Tatyana, Ivanov, Gleb, Zhumagalieva, Aisulu, Garabadzhiu, Alexa

Journal:

Bioorganic & Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 2.05 MB

english, 2018

24

Hydroxylamine as an ammonia equivalent: access to NH-tetrahydroisoquinolonic derivatives from aldoximes by the Castagnoli–Cushman reaction followed by reduction

Bannykh, Anton V., Bakulina, Olga Yu., Dar’in, Dmitry V., Krasavin, Mikhail

Journal:

Mendeleev Communications

Year:

2019

Language:

english

File:

PDF, 283 KB

english, 2019

25

The first solvent-free synthesis of privileged gamma- and delta-lactams via the Castagnoli-Cushman reaction

Lepikhina, Anastasia, Bakulina, Olga, Dar'in, Dmitry, Krasavin, Mikhail

Journal:

Year:

2016

Language:

english

File:

PDF, 725 KB

english, 2016

26

Unusually Reactive Cyclic Anhydride Expands the Scope of the Castagnoli–Cushman Reaction

Chizhova, Maria, Khoroshilova, Olesya, Dar’in, Dmitry, Krasavin, Mikhail

Journal:

Journal of Organic Chemistry

Year:

2018

Language:

english

File:

PDF, 718 KB

english, 2018

27

ChemInform Abstract: Diversity-Oriented Pyrazol-3-one Synthesis Based on Hydrazinodipeptide-Like Units Prepared via the Ugi Reaction.

Ekaterina Lakontseva, Mikhail Krasavin

Journal:

Year:

2010

File:

PDF, 47 KB

2010

28

ChemInform Abstract: Cyclic Products of the Ugi Reaction of Aldehydo and Keto Carboxylic Acids: Chemoselective Modification.

Alan Tsaloev, Alexei Ilyin, Sergey Tkachenko, Alexandre Ivachtchenko, Dmitry Kravchenko, Mikhail Krasavin

Journal:

Year:

2011

File:

PDF, 33 KB

2011

29

ChemInform Abstract: Microwave-Assisted aza-Prins Reaction. Part 1. Facile Preparation of Natural-Like 3-Azabicyclo[3.3.1]non-6-enes.

Vladislav Parchinsky, Alexei Shumsky, Mikhail Krasavin

Journal:

Year:

2012

File:

PDF, 27 KB

2012

30

Convenient access to novel functionalized pyrazino[1,2-b]isoquinolin-6-one and diazepino[1,2-b]isoquinolin-7-one scaffolds via the Cushman multicomponent reaction followed by post-condensation

Sarnpitak, Pakornwit, Krasavin, Mikhail

Journal:

Tetrahedron Letters

Year:

2014

Language:

english

File:

PDF, 865 KB

english, 2014

31

Antiproliferative 4-(1,2,4-oxadiazol-5-yl)piperidine-1-carboxamides, a new tubulin inhibitor chemotype

Krasavin, Mikhail, Sosnov, Andrey V., Karapetian, Ruben, Konstantinov, Igor, Soldatkina, Olga, Godovykh, Elena, Zubkov, Fedor, Bai, Ruoli, Hamel, Ernest, Gakh, Andrei A.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2014

Language:

english

File:

PDF, 3.06 MB

english, 2014

32

tert-Butyl Isocyanide as a Convertible Reagent in Ugi Reaction: Microwave-Assisted Preparation of 5,6-Dihydropyrazolo[1,5-a]pyrazine-4,7-diones

Nikulnikov, Mikhail, Tsirulnikov, Sergey, Kysil, Volodymyr, Ivachtchenko, Alexandre, Krasavin, Mikhail

Journal:

Year:

2009

Language:

english

File:

PDF, 82 KB

english, 2009

33

Free fatty acid receptor 1 (GPR40) agonists containing spirocyclic periphery inspired by LY2881835

Krasavin, Mikhail, Lukin, Alexey, Bagnyukova, Daria, Zhurilo, Nikolay, Zahanich, Ihor, Zozulya, Sergey, Ihalainen, Jouni, Forsberg, Markus M., Lehtonen, Marko, Rautio, Jarkko, Moore, Daniel, Tikhonova

Journal:

Bioorganic & Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 708 KB

english, 2016

34

Facile entry into structurally diverse, privileged, (hetero)arene-fused N-alkoxy 3,4-dihydrobenzo[f][1,4]oxazepin-5(2H)-ones

Sapegin, Alexander, Reutskaya, Elena, Smirnov, Alexey, Korsakov, Mikhail, Krasavin, Mikhail

Journal:

Tetrahedron Letters

Year:

2016

Language:

english

File:

PDF, 590 KB

english, 2016

35

1,2,4-Oxadiazole/2-Imidazoline Hybrids: Multi-target-directed Compounds for the Treatment of Infectious Diseases and Cancer

Shetnev, Anton, Baykov, Sergey, Kalinin, Stanislav, Belova, Alexandra, Sharoyko, Vladimir, Rozhkov, Anton, Zelenkov, Lev, Tarasenko, Marina, Sadykov, Evgeny, Korsakov, Mikhail, Krasavin, Mikhail

Journal:

International Journal of Molecular Sciences

Year:

2019

File:

PDF, 5.62 MB

2019

36

N-Alkylation of Nitrogen Heterocycles with Î±-Diazocarbonyl Compounds

Solovyev, Igor V., Zhukovsky, Daniil D., Darâin, Dmitry V., Krasavin, Mikhail Yu.

Journal:

Chemistry of Heterocyclic Compounds

Year:

2020

File:

PDF, 333 KB

2020

37

Diazo Glutaconimides: an Unexplored Type of Heterocyclic Î±âDiazocarbonyl Compounds Conveniently Evolved into Pyridineâ2,6(1 H ,3 H )âdiones and Oxazolo[5,4â b ]pyridinâ5(4 H )âones

Guranova, Natalia, Kantin, Grigory, Dar'in, Dmitry, Krasavin, Mikhail

Journal:

European Journal of Organic Chemistry

Year:

2020

File:

PDF, 2.24 MB

2020

38

ChemInform Abstract: Hydrazinopeptide Motifs Synthesized via the Ugi Reaction: An Insight into the Secondary Structure.

Mikhail Krasavin, Ekaterina Bushkova, Vladislav Parchinsky, Alexei Shumsky

Journal:

Year:

2010

File:

PDF, 41 KB

2010

39

Panel docking of small-molecule libraries — Prospects to improve efficiency of lead compound discovery

Sarnpitak, Pakornwit, Mujumdar, Prashant, Taylor, Paul, Cross, Megan, Coster, Mark J., Gorse, Alain-Dominique, Krasavin, Mikhail, Hofmann, Andreas

Journal:

Biotechnology Advances

Year:

2015

Language:

english

File:

PDF, 1.32 MB

english, 2015

40

Indoline-Based Constrained Peptidomimetic Motifs Obtained via the Joullié-Ugi Reaction of Indolenines

Golubev, Pavel, Bakulina, Olga, Dar'in, Dmitry, Krasavin, Mikhail

Journal:

European Journal of Organic Chemistry

Year:

2016

Language:

english

File:

PDF, 1.48 MB

english, 2016

41

Phosphorescent Platinum(II) Complexes Featuring Chelated Acetoxime Pyrazoles: Synthetic, Structural, and Photophysical Study

Bolotin, Dmitrii S., Novikov, Alexander S., Kolesnikov, Ilya E., Suslonov, Vitaliy V., Novozhilov, Yuri, Ronzhina, Oksana, Dorogov, Mikhail, Krasavin, Mikhail, Yu. Kukushkin, Vadim

Journal:

ChemistrySelect

Year:

2016

Language:

english

File:

PDF, 1.02 MB

english, 2016

42

Rh(II)-catalyzed Cycloaddition of alpha-Diazo Homophthalimides and Nitriles Delivers Novel Oxazolo[5,4-c]isoquinolin-5(4H)-one Scaffold

Kantin, Grigory, Dar'in, Dmitry, Krasavin, Mikhail

Journal:

European Journal of Organic Chemistry

Year:

2018

Language:

english

File:

PDF, 1.12 MB

english, 2018

43

Dual use of propargylamine building blocks in the construction of polyheterocyclic scaffolds

Bakholdina, Anna, Lukin, Alexei, Bakulina, Olga, Guranova, Natalia, Krasavin, Mikhail

Journal:

Tetrahedron Letters

Year:

2020

File:

PDF, 782 KB

2020

44

ChemInform Abstract: Dihydro-resveratrol—A Potent Dietary Polyphenol.

Andrei A. Gakh, Natalia Yu Anisimova, Mikhail V. Kiselevsky, Sergey V. Sadovnikov, Ivan N. Stankov, Mikhail V. Yudin, Konstantin A. Rufanov, Mikhail Yu Krasavin, Andrey V. Sosnov

Journal:

Year:

2011

File:

PDF, 21 KB

2011

45

Poorly reactive 5-piperazin-1-yl-1,3,4-thiadiazol-2-amines rendered as valid substrates for Groebke–Blackburn type multi-component reaction with aldehydes and isocyanides using TMSCl as a promoter

Mikhail Krasavin, Sergey Tsirulnikov, Mikhail Nikulnikov, Volodymyr Kysil, Alexandre Ivachtchenko

Journal:

Tetrahedron Letters

Year:

2008

Language:

english

File:

PDF, 165 KB

english, 2008

46

Antimalarial, Antiproliferative, and Antitumor Activities of Artemisinin-Derived, Chemically Robust, Trioxane Dimers

Posner, Gary H., Ploypradith, Poonsakdi, Parker, Michael H., O'Dowd, Hardwin, Woo, Soon-Hyung, Northrop, John, Krasavin, Mikhail, Dolan, Patrick, Kensler, Thomas W., Xie, Suji, Shapiro, Theresa A.

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 100 KB

english, 1999

47

Natural products as templates for bioactive compound libraries: Part 2. Novel modifications of vasicine (peganine) core via efficient and regioselective generation of 3-lithiodeoxyvasicine and its stereoselective addition to aliphatic ketones§

Shevyakov, Sergey V., Davydova, Olga I., Kiselyov, Alex S., Kravchenko, Dmitry V., Ivachtchenko, Alexandre V., Krasavin, Mikhail

Journal:

Natural Product Research

Year:

2006

Language:

english

File:

PDF, 169 KB

english, 2006

48

Practical Outcome of Azaphthalimide Reduction with Zn/AcOH at Various Temperatures

Krasavin, Mikhail, Kravchenko, Dmitry, Talismanova, Tatiana, Koleda, Vladimir, Ushakova, Olga, Parchinsky, Vladislav

Journal:

Letters in Organic Chemistry

Year:

2006

Language:

english

File:

PDF, 62 KB

english, 2006

49

ChemInform Abstract: A Simple, Three-Component Synthesis of 2-Aminothiazoles Using Trimethylsilyl Isothiocyanate.

Golubev, Viktor, Zubkov, Fedor, Krasavin, Mikhail

Journal:

Year:

2014

File:

PDF, 31 KB

2014

50

ChemInform Abstract: The Rare cis-Configured Trisubstituted Lactam Products Obtained by the Castagnoli-Cushman Reaction in N,N-Dimethylformamide.

Dar'in, Dmitry, Bakulina, Olga, Nikolskaya, Sofia, Gluzdikov, Ivan, Krasavin, Mikhail

Journal:

Year:

2016

File:

PDF, 28 KB

2016

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